Associations Between B Vitamin Interactions with Polyunsaturated Fatty Acids and Cognitive Function Among Cognitively Healthy Older People as Modified by Amyloid Status and Sex.

Conversely, the synergistic effect between PUFAs and B12 displayed a similar pattern to that of PUFAs alone, showing a positive trend in the amyloid-positive group (except attention), significance for delayed memory in Model 1, while revealing a negative but non-significant trend in the amyloid-negative group.

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The interaction effects between PUFAs and folic acid followed a similar pattern to that of folate intake alone, with cognitive scores exhibiting a negative trend in the amyloid-positive group.

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