Clinical and genetic landscape of optic atrophy in 826 families: insights from 50 nuclear genes.

When comparing the BCVA among the optic atrophy, LHON-like and optic atrophy plus retinal degeneration groups, the latter manifested a worse BCVA than the optic atrophy and LHON-like groups, although the difference in BCVA between the optic atrophy plus retinal degeneration and LHON-like groups did not reach statistical significance ( Supplementary Fig. 5 ).

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