Barely Significant
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CCL2 blockade combined with PD-1/P-selectin immunomodulators impedes breast cancer brain metastasis.

Brain · 2025 · PMC12073999 · PMID 39450648

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showed a trendno p-value reported
50 Although not reaching statistical significance, all three markers, CCL2, CCR2 and CCR4, showed a trend towards higher expression in the tumours that later metastasized to the brain ( Fig. 2K–M ).

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