Barely Significant
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Major Adverse Cardiovascular Events in Primary Aldosteronism After Adrenalectomy or Mineralocorticoid Receptor Antagonist Treatment: A Systematic Review and Meta-Analysis.

J Am Heart Assoc · 2025 · PMC12074773 · PMID 39895534

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an observed trendno p-value reported
Similarly, there was an observed trend indicating that patients with PA with posttreatment PRA levels between 1 and 2 ng/mL per hour had a lower incidence of MACE compared with those with PRA levels either <1 ng/mL per hour or >2 ng/mL per hour; however, this trend also did not reach statistical significance.

also in 249 other papers

Similarly, there was an observed trend indicating that patients with PA with posttreatment PRA levels between 1 and 2 ng/mL per hour had a lower incidence of MACE compared with those with PRA levels either <1 ng/mL per hour or >2 ng/mL per hour; however, this trend also did not reach statistical significance.

also in 53,799 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.