Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome.

Front Pharmacol · 2025 · PMC12075540 · PMID 40371354

Europe PMC DOI

hedged sentence

0.0990

closest p · 2.0× alpha

0.0990

boldest claim

The sentences

did not reach statistical significancep = 0.099so close (0.05 < p ≤ 0.1)

Among the 11 patients with MRI abnormalities (including periventricular leukomalacia or corpus callosum dysgenesis), IGF-1 levels (35.96 ± 15.53, [range 17.20–66.20] ng/mL) were lower than those in patients with non-structural etiologies (49.38 ± 16.46, [range 19.90–79.30] ng/mL), though this difference did not reach statistical significance (p = 0.099).

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