Impact of Opioid and Cannabis Use on Low-Dose Amitriptyline Efficacy in Cyclical Vomiting Syndrome: A Real-World Study in the United Kingdom.

Neurogastroenterol Motil · 2025 · PMC12075911 · PMID 40017095

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Although this did not reach statistical significance in the multivariate logistic regression model ( p = 0.07), this finding still implies that anti‐emetics positively influenced the effectiveness of the treatment algorithm.

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