9 , 30 The STABLE-SR trial found significant benefits in PeAF patients, but the results of the subsequent STABLE-SR–II trial failed to reach statistical significance. 21 , 31 These trials reconfirmed CPVI as the cornerstone for AF ablation in patients without LVAs, while leaving additional LVA modification in patients with LVAs controversial.
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Persistent atrial fibrillation with left atrial low-voltage area: who benefit from additional modification?
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