The Human Leukocyte Antigen (HLA) DRB1*13:02 Allele Protects against Dementia in Continental Western Europe.

J Neurol Neuromedicine · 2019 · PMC12077165 · PMID 40371383

Europe PMC DOI

hedged sentences

0.1610

closest p · 3.2× alpha

0.1610

boldest claim

The sentences

did not reach statistical significanceP = 0.161not close (p > 0.1)

Effect of DRB1*13:01 on dementia prevalence Dementia prevalence decreased with increasing frequency of DRB1*13:01 but this relation did not reach statistical significance (R 2 = 0.157, P = 0.161; exponential fit); the partial correlation of dementia prevalence vs.

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highly significantno p-value reported

In addition, this effects was independent of apoE4 prevalence since it was still present and highly significant when the effect of apoE4 prevalence was partialed out; specifically, the partial correlation of dementia prevalence vs DRB1*13:02 frequency, accounting for apoE4 prevalence, was −0.782, P = 0.002).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.