The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles.

Gut Microbes · 2025 · PMC12077474 · PMID 40355382

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In addition, the number of large Aβ plaque-associated microglia in the hippocampus of GF housed App NL-G-F AD mice showed a trend toward reduction upon administration of SPF housed App NL-G-F bEVs ( Figure 6(c,d) ).

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