DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function.

Nat Commun · 2025 · PMC12078682 · PMID 40368879

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did not reach statistical significanceno p-value reported

The DG9-conjugated PMO treatment group showed a decrease in collagen deposition to 103.3%, which, while improved, did not reach statistical significance compared to the WT or unconjugated PMO (111.3%) treatment groups, as shown in Supplementary Fig. 8 .

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