iMSCs were seeded on the mixed PDMS substrates as described before, using only the 184, 10:1 1:1, 1:10, and 527 groups, as the differences in the elastic moduli were pronounced enough to still observe a clear trend in angiogenic activity.
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Mesenchymal stem cell extracellular vesicle vascularization bioactivity and production yield are responsive to cell culture substrate stiffness.
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