49.8%), however this did not reach statistical significance. 37 Kocsis et al. 7 compared POU4F3 methylation to cytology in over 1200 HPV positive women and reported a higher sensitivity (70.1% vs. 42.7%) with a similar specificity (81.4% vs. 80.4%) for CIN2+. 14 Chang et al. 38 compared PAX1 methylation to cytology and HPV 16/18 genotyping in a Taiwanese screening population of 429 hrHPV positive women.
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DNA methylation signatures of cervical pre-invasive and invasive disease: An epigenome-wide association study.
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