Influence of the metabolic and inflammatory profile in patients with frozen shoulder - systematic review and meta-analysis.

BMC Musculoskelet Disord · 2025 · PMC12079921 · PMID 40375116

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

a trend toward significancep = 0.062so close (0.05 < p ≤ 0.1)

Meta-regressions showed that the ratio between FS and control group sizes had a trend toward significance ( p = 0.062), suggesting that studies with a more balanced distribution report larger effects, while publication year, sample size, and mean age of participants showed no significant impact.

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did not reach statistical significanceno p-value reported

[ 28 ] identified elevated levels of inflammatory and fibrotic cytokines in the synovial membrane of FS patients compared to controls, although differences in MMP-3 ( p = 0.068) and IL-6 ( p = 0.062) did not reach statistical significance.

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