Comparative metabolomics of two nettle species unveils distinct high-altitude adaptation mechanisms on the Tibetan Plateau.

In contrast, Cluster 6 (174 metabolites) displayed a decreasing trend, dominated by 39 lipids and lipid-like molecules, 16 amino acids, peptides, and analogues, and 16 terpenoids (Fig. 6 C).

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In the present study, carbohydrates and carbohydrate conjugates in both species exhibited a significant trend of enrichment at high altitudes.

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