Barely Significant
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Transcriptomics of Anterior Shoulder Instability: Differences in Gene Expression in the Blood of Patients With and Without Significant Glenoid Bone Loss.

Orthop J Sports Med · 2025 · PMC12081967 · PMID 40386647

2
hedged sentences
0.7000
closest p · 14.0× alpha
0.7000
boldest claim

The sentences

did not reach statistical significanceP = .70not close (p > 0.1)
P values for the other genes did not reach statistical significance ( IFI44: P = .70; IFIT1: P = .42; OAS2: P = .69; PRKCB: P = .59), suggesting that specific gene isoforms captured by nCounter but not qPCR could be involved.

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highly significantno p-value reported
Additionally, rigorous scientific and statistical methods were followed with the confirmation of RNA quality with high RIN values, confirmation of gene expression results with nonparametric methods, highly significant P values (.000013, .00011, .0001, .00019, and .0006), and strict quality control measures for the nCounter.

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