CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro.

Bone Joint Res · 2025 · PMC12082574 · PMID 40376984

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showed a trendno p-value reported

The expression of CXCR4 in response to TPTD was also evaluated at a protein level in MC3T3 differentiated osteoblasts treated with the drug for 24 hours; results showed a trend to increased CXCR4 levels (median = 2 (IQR 1.4 to 2.5)) (Supplementary Figure c).

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