Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study.

BMC Pregnancy Childbirth · 2025 · PMC12084962 · PMID 40380151

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did not reach statistical significanceno p-value reported

Notably, while the increase in amniotic fluid CSE levels did not reach statistical significance, maternal serum CSE levels were significantly higher in Down syndrome cases compared to controls, with an approximately twofold increase.

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