Safety and cognitive pharmacodynamics following dose escalations with 3-methylmethcathinone (3-MMC): a first in human, designer drug study.

Neuropsychopharmacology · 2025 · PMC12089282 · PMID 39719487

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

approached significancep = 0.059so close (0.05 < p ≤ 0.1)

The main effect of Dose on temperature approached significance (F 3,90.448 = 2.577, p = 0.059) and did not interact with Time.

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failed to reach significanceno p-value reported

Dose effects on hunger (F 3,55.753 = 2.450, p = 0.073) and appetite (F 3,75.681 = 2.582, p = 0.060) failed to reach significance.

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