Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.

Nat Commun · 2025 · PMC12089458 · PMID 40389397

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showed a trendno p-value reported

Only the TARDBP M337V line showed a trend towards lower substrate oxidation (Supplementary Fig. 9f ).

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