In T1DM we found a similar trend, but this did not reach statistical significance ( Fig 2 ).
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Microbiome and pediatric leukemia, diabetes, and allergies: Systematic review and meta-analysis.
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We also performed an analysis including only those studies that measured microbiome at the time of T1DM diagnosis which is more similar to the design of the ALL studies meta-analysis and shows a slight trend in the same direction as the overall analysis (S5 Fig in S1 File ).