Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease.

Nat Commun · 2025 · PMC12092707 · PMID 40393978

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did not reach statistical significanceno p-value reported

Lung IL-12 family cytokines and IFNβ were significantly higher in Polg D257A mice at the 24-h harvest point following re-infection, while other cytokines were trending higher in Polg D257A mice, although they did not reach statistical significance (Supplementary Fig. 16c ).

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