Genes with more accessible promoters in KD saline showed a trend for increased expression (FDR = 0.123, Fig. 5b ), while genes with less accessible promoters were significantly more likely to have decreased gene expression (FDR = 0.008, Fig. 5c ).
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Silencing <i>TET1</i> expression alters the epigenomic landscape and amplifies transcriptomic responses to allergen in airway epithelial cells.
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