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GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male mice.

Nat Commun · 2025 · PMC12095689 · PMID 40399267

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Fasting glucose of cotadutide-treated mice trended lower than vehicle perhaps reflecting increased basal glucose excursion but failed to reach statistical significance (Fig. 1B ).

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