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Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism.

Adv Sci (Weinh) · 2025 · PMC12097039 · PMID 39965080

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slightly significantp = 7.10 −8actually significant
Auditory spectrotemporal receptive fields (STRFs) (Figure 9C,Di ) were only moderately affected in Otogl +/− mutant mice relative to Otogl +/+ controls, with a slightly significant change in response latency ( p = 7.10 −8 , nested two‐way ANOVA, group effect, animal factor nested in group, F(1,1379) = 29.5) and a 5.8% decrease in frequency bandwidth ( p = 0.048, nested ANOVA, F(1,1379) = 3.9), with no change in maximum evoked firing rate ( p = 0.06, nested ANOVA, F(1,1379) = 3.5).

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