Barely Significant
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Sex differences in amyloid PET in a large, real-world sample from the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study.

Alzheimers Dement · 2025 · PMC12104074 · PMID 40415175

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0.0550
closest p · 1.1× alpha
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boldest claim

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did not reach statistical significancep = 0.055so close (0.05 < p ≤ 0.1)
The interaction between sex and CLs did not reach statistical significance in correlations with MMSE ( p = 0.055; Figure 3 ). 4 DISCUSSION Our analysis of a large, real‐world, memory clinic–based cohort of Medicare beneficiaries presenting with MCI or dementia revealed that females had significantly higher proportions and odds of amyloid PET positivity, along with a greater global amyloid burden (CL) compared to males, irrespective of cognitive impairment severity.

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