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CD248 deficiency promotes angiotensin II-induced aortic lesion by attenuating receptor stability in smooth muscle cells.

Clin Transl Med · 2025 · PMC12104565 · PMID 40415469

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Quantification showed that 1 of 13 (7.69%) Cd248 +/+ mice developed a thoracic aortic lesion, whereas 5 of 16 (31.25%) Cd248 −/− mice developed thoracic aortic lesion, but the difference did not reach statistical significance (Figure S4A–L ).

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