did not reach statistical significancep = 0.0577
Regarding OS, the TT/BU group exhibited a trend toward improved outcomes, with the median OS not reached (95% confidence interval: 296-NA) and a 3 year OS of 80.0% (95% confidence interval: 20.4–96.9), compared to a median OS of 234 days (95% confidence interval: 56-NA) and a 3 year OS of 42.9% (95% confidence interval: 9.8–73.4) in the alternative regimen group although the difference did not reach statistical significance ( p = 0.0577) (Supplementary Fig. 2B).