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Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra-performance liquid chromatography.

Animal Model Exp Med · 2025 · PMC12107366 · PMID 39868846

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showed a trendno p-value reported
We found that the concentration of each component to be measured showed a trend of first increasing and then decreasing, on the drug time curve, which indicated the process of absorption, distribution, and metabolic elimination of drug components in the body and conformed to the typical oral metabolism characteristics of drugs.

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