As shown in Figure 4 A, the inclusion of the five most relevant metabolites based on VIP score (leucine, asparagine, alanine, cysteine, and creatine) to the classic model (age, BMI, and waist circumference) resulted in a significant increase in the AUC compared to the PF group (from 78% to 100%), although this difference did not reach statistical significance.
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Impact of Combined Macronutrient Diet on Amino Acids and Amines Plasma Levels.
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