Antipyretic Mechanism of Bai Hu Tang on LPS-Induced Fever in Rat: A Network Pharmacology and Metabolomics Analysis.

The results show that the curve overlap of the total ion flux for metabolite detection is high, i.e., the retention time and peak intensity are consistent, indicating that the mass spectrometry has good signal stability when the same sample is detected at different times, and that the high stability of the instrument provides an important guarantee for the reproducibility and reliability of the data; by performing Principal Component Analysis on the total samples of the experiment (including the quality control samples), the PCA results showed a trend of metabolome separation between the groups, indicating that there were significant differences in metabolomes between the sample groups, and the differences were significant ( p < 0.05), indicating that the data modelling was reasonable and could be used for PCA analysis of the samples, the correl

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