Dynamic Interaction Between SARS-CoV-2 and Influenza A Virus Infection in Human Respiratory Tissues and Cells.

There was an elevated trend in IFN-λ1, IL-6, ISG15, and MCP-1 expression with H3N2 (4550) infection, which were suppressed upon co-infection with SCoV2/BA.1.

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Sequential Infection of SCoV2 and Influenza A in Airway and Alveolar Epithelial Cells Sequential infection with SCoV2 and then influenza virus at 24 hpi in the airway epithelial cells showed a trend of reduction in SCoV2 replication during co-infection, particularly co-infection with H5N1, without statistical significance, while there was no change in the replication of the influenza viruses ( Figure 9 a,b and Figure S2e ).

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