Barely Significant
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Vitamin C Transport Deficiency Alters Striatal Dopamine Gene Expression and Metabolism in YAC128 Huntington Disease Mice.

Genes Brain Behav · 2025 · PMC12116213 · PMID 40425486

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

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approaching significancep = 0.06so close (0.05 < p ≤ 0.1)
No genes were significantly and substantially upregulated in SVCT2 +/− striatal tissue compared to WT, although dopamine receptor D2 (Drd2) was upregulated 2.05‐fold with a p value approaching significance ( p = 0.06) (Figure 2A and Table 2 ).

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