Association between the systemic immune-inflammatory index and the immune response after hepatitis B vaccination: a cross-sectional analysis of NHANES data.

Front Public Health · 2025 · PMC12116451 · PMID 40438079

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a decreasing trendno p-value reported

A cross-sectional survey from rural China revealed that, after 20–31 years of primary vaccination with a plasma-derived hepatitis B vaccine, the average positive rate of anti-HBs was 53.21%, and a decreasing trend was observed ( 59 ).

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did not reach statistical significanceno p-value reported

In Model 2, this trend persisted; however, it did not reach statistical significance.

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