Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lipid remodeling in lung adenocarcinoma progression.

Nat Commun · 2025 · PMC12117057 · PMID 40425563

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0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Moreover, increased concentrations of major endogenous metabolites of palmitate desaturation, palmitoleic and oleic acids, also indirectly confirmed palmitate excess, although palmitoleic acid levels did not reach statistical significance ( p = 0.09, Fig. 6c, d ).

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