The contribution of cyclic imide stereoisomers on cereblon-dependent activity.

Chem Sci · 2025 · PMC12117711 · PMID 40443985

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did not reach statistical significanceno p-value reported

The monoubiquitination levels of GFP-FcQ, GFP-FepicQ, GFP-FcN and GFP-FepicN with K0-ubiquitin were 4.8, 2.4, 7.1 and 1.3-fold greater than methylated GFP-FcQ (GFP-FcQMe), respectively, although the fold change of GFP-FepicN did not reach statistical significance ( Fig. 5d ).

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