Establishing a context of use for three-dimensional cardiac tissue derived from human-induced pluripotent stem cell-derived cardiomyocytes using inotropes.

Toxicol Sci · 2025 · PMC12118959 · PMID 40220331

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showed a trendno p-value reported

Amrinone (a PDE3 inhibitor) showed a trend toward an increase in active force at 30 μM in the 3D ECTs, though this change was not statistically significant ( Fig. 2G ).

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