Metabolic parameters on baseline and early [<sup>18</sup>F]FDG PET/CT as a predictive biomarker for resistance to BRAF/MEK inhibition in advanced cutaneous BRAFV600-mutated melanoma.

EJNMMI Res · 2025 · PMC12119442 · PMID 40434500

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did not reach statistical significanceno p-value reported

Although baseline CoV and changes at 7 weeks did not reach statistical significance, the observed trends suggest a potential role of heterogeneity dynamics as an early biomarker of treatment efficacy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Metabolic parameters on baseline and early [&lt;sup&gt;18&lt;/sup&gt;F]FDG PET/CT as a predictive biomarker for resistance to BRAF/MEK inhibition in advanced cutaneous BRAFV600-mutated melanoma.

The sentences

Metabolic parameters on baseline and early [<sup>18</sup>F]FDG PET/CT as a predictive biomarker for resistance to BRAF/MEK inhibition in advanced cutaneous BRAFV600-mutated melanoma.