Efficacy and toxicity of stereotactic radiotherapy combined with third-generation EGFR-TKIs and immunotherapy in patients with brain metastases from non-small cell lung cancer.

Strahlenther Onkol · 2025 · PMC12119770 · PMID 40009081

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did not reach statistical significanceno p-value reported

In this study, the 1‐year PFS of local irradiated sites in patients with NSCLC BM treated using SRT and third-generation EGFR-TKIs was 88.01% (HR: 0.556, 95% CI [0.221–1.394], P = 0.210), which suggest a trend effect, but did not reach statistical significance.

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