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Safety of sulfamethoxazole-trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta-analysis with active comparator disproportionality analysis.

Br J Clin Pharmacol · 2025 · PMC12122145 · PMID 40441678

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A higher risk of rash was also observed when penicillin or other sulfonamide‐TMP combinations were used as the comparator group, but the difference did not reach statistical significance (Figure 3B,C ).

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