Development and characterisation of a novel 3D in vitro model of obesity-associated breast cancer as a tool for drug testing.

NPJ Breast Cancer · 2025 · PMC12125370 · PMID 40447655

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an observed trendno p-value reported

As HA spheroids showed significantly enhanced lipolytic activity compared to MA, which was only an observed trend in 2D culture, this may suggest that 3D spheroid culture of adipocytes are a more suitable method of generating HA.

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showed a trendno p-value reported

However, HA showed a trend towards increased FAO compared to MA (Fig.

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