Hypercholesterolemia Duration and Brain Area Determine Inflammatory Response Intensity and Apoptotic Mediator Activation in Apo E<sup>-/-</sup>/LDLR<sup>-/-</sup> Double-Knockout Mice.

Cell Mol Neurobiol · 2025 · PMC12125462 · PMID 40445431

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a strong trendno p-value reported

These changes were accompanied by a reduction in the anti-inflammatory IL-4 in Hch mice at 3 and 12 months of age (with a strong trend observed in the 6-month-old mice).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Hypercholesterolemia Duration and Brain Area Determine Inflammatory Response Intensity and Apoptotic Mediator Activation in Apo E&lt;sup&gt;-/-&lt;/sup&gt;/LDLR&lt;sup&gt;-/-&lt;/sup&gt; Double-Knockout Mice.

The sentences

Hypercholesterolemia Duration and Brain Area Determine Inflammatory Response Intensity and Apoptotic Mediator Activation in Apo E<sup>-/-</sup>/LDLR<sup>-/-</sup> Double-Knockout Mice.