Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East Asians.

Nat Commun · 2025 · PMC12126482 · PMID 40450010

Europe PMC DOI

hedged sentence

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

approaching significanceP = 0.086so close (0.05 < p ≤ 0.1)

To further validate this association, we assessed rs75326924 in an independent GWAS of a Korean cohort [19], observing a similar effect direction (BETA = −0.54) with a P -value approaching significance ( P = 0.086).

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