MACanalyzeR scRNAseq analysis tool reveals PPARγ<sup>HIGH</sup>/GDF15<sup>HIGH</sup> lipid-associated macrophages facilitate thermogenic expansion in BAT.

Nat Commun · 2025 · PMC12126529 · PMID 40450001

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a significant trendno p-value reported

Subsequent comparison of the two HFD models, WT and MAC PPARGKO , revealed a significant trend towards greater weight gain in KO mice compared to the WT.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

MACanalyzeR scRNAseq analysis tool reveals PPARγ&lt;sup&gt;HIGH&lt;/sup&gt;/GDF15&lt;sup&gt;HIGH&lt;/sup&gt; lipid-associated macrophages facilitate thermogenic expansion in BAT.

The sentences

MACanalyzeR scRNAseq analysis tool reveals PPARγ<sup>HIGH</sup>/GDF15<sup>HIGH</sup> lipid-associated macrophages facilitate thermogenic expansion in BAT.