Dual Glucagon-Like Peptide-1 (GLP-1) and Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Agonist-Associated Thyroiditis: A Case Report of Thyroid Dysfunction Following Tirzepatide Use.

Cureus · 2025 · PMC12127604 · PMID 40458348

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did not reach statistical significanceno p-value reported

For example, a meta-analysis of 45 randomized controlled trials observed a trend toward increased risk of thyroid dysfunction in patients treated with GLP-1 receptor agonists, although the findings did not reach statistical significance.

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