High immunoproteasome and low constitutive proteasome subunit levels correlate with sensitivity to bortezomib-containing chemotherapy: update from the Children's Oncology Group AALL1231 trial.

Haematologica · 2025 · PMC12130773 · PMID 39882653

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

did not reach statistical significanceP =0.058so close (0.05 < p ≤ 0.1)

For the β5i/β5-ratio this did not reach statistical significance ( P =0.058; Online Supplementary Figure S2D ) probably due to the late event after 4 years (off-therapy death).

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