Reply to Füller et al.: Exome-wide genetic associations with socioeconomic status and their pleiotropy among health outcomes.

Proc Natl Acad Sci U S A · 2025 · PMC12130888 · PMID 40378011

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hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP < 0.05actually significant

We selectively included 44 diseases (excluding cancer, which is a limitation to be noted) in the first part of phenome-wide association analysis (PheWAS) and identified nominally significant associations ( P < 0.05) between the SES-associated variants and CHD.

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