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EBV Reactivation-associated gene signature predicts poor prognosis in nasopharyngeal carcinoma.

J Transl Med · 2025 · PMC12131606 · PMID 40457434

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Although these trends did not reach statistical significance—likely due to sample size limitations—they suggest that elevated pEBV DNA levels, reflecting EBV reactivation, may contribute to increased tumor recurrence, enhanced metastatic potential, and more aggressive NPC progression.

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