Long-term clinical outcomes of oral anticoagulation in the older patients with atrial fibrillation aged ≥80 years: a report from the GLORIA-AF registry phase III.

Although the rate of major bleeding was lower in the group of dabigatran than in the warfarin group, the association of dabigatran and a reduction risk of major bleeding did not reach statistical significance after multivariate adjustment, consistent with previous reports suggesting that dabigatran may carry a similar risk of extracranial bleeding in the older patients to warfarin [ 52 ].

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