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Evaluation of the therapeutic effects of the topical and systemic forms of Honokiol in 5-fluorouracil-induced oral mucositis model in rats.

Sci Rep · 2025 · PMC12134167 · PMID 40461551

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Although they did not reach statistical significance, the OSI values, which is an indicator of oxidative load, were lower than in the topical (23.87 ± 15.48) and systemic honokiol (28.78 ± 20.72) groups compared to the vehicle (29.47 ± 20.63) and control (39.41 ± 23.65) groups.

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