Similar to the epigenetic effects of short-term IL preactivation, methylome profiles of surviving long-term IL-12/15/18 preactivated NK cells showed a trend toward subtle hypomethylation, which was not significantly different from profiles of low dose IL-15 stimulated NK cells ( Fig. 1A ; Supplementary Fig.
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Memory-like Natural Killer Cell and CD19 Antibody-Based Immunotherapy in Combination with Tyrosine Kinase Inhibition Has Antitumor Effects against Ph(-like) Acute Lymphoblastic Leukemia.
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